Guillotine League Strategy: Tips & Rankings for 2025 Fantasy Football Drafts

Avoid getting chopped from your guillotine league with these eight strategies and player rankings to build a winning roster and team.
Guillotine League Strategy: Tips & Rankings for 2025 Fantasy Football Drafts
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Each of the past two seasons I have written an article like this, where I share my guillotine league strategy and give examples of players to target and others to avoid. Naturally, I end up with a fair share of both hits and misses. I can take a victory lap for recommending Baker Mayfield, Chase Brown and Jaxon Smith-Njigba, while advising to avoid Marvin Harrison, Jonathon Brooks and Hollywood Brown last season. On the flipside, I did say not to buy Malik Nabers or Brock Bowers at cost.

Despite the misses, my strategy isn't changing in 2025. I will still favor players I view as proven "safe" players over more potentially volatile players. After all, with a guillotine league the goal isn't necessarily to have the best team; it's about not having the worst team any given week. There's no reason to take big risks.

What is a Guillotine League?

In a guillotine league, you're not matched up against a single opponent each week. Instead, you're competing against the entire league. The goal is straightforward: avoid finishing last. Each week, the team with the lowest score is eliminated, and their players are released to waivers, giving the remaining teams a chance to claim them. This continues weekly until only one team is left standing — the champion.

Most guillotine leagues begin with 16 or 17 teams, without divisions or a fixed schedule, though you can adjust the league's size and timing based on preferences. While some fantasy

Each of the past two seasons I have written an article like this, where I share my guillotine league strategy and give examples of players to target and others to avoid. Naturally, I end up with a fair share of both hits and misses. I can take a victory lap for recommending Baker Mayfield, Chase Brown and Jaxon Smith-Njigba, while advising to avoid Marvin Harrison, Jonathon Brooks and Hollywood Brown last season. On the flipside, I did say not to buy Malik Nabers or Brock Bowers at cost.

Despite the misses, my strategy isn't changing in 2025. I will still favor players I view as proven "safe" players over more potentially volatile players. After all, with a guillotine league the goal isn't necessarily to have the best team; it's about not having the worst team any given week. There's no reason to take big risks.

What is a Guillotine League?

In a guillotine league, you're not matched up against a single opponent each week. Instead, you're competing against the entire league. The goal is straightforward: avoid finishing last. Each week, the team with the lowest score is eliminated, and their players are released to waivers, giving the remaining teams a chance to claim them. This continues weekly until only one team is left standing — the champion.

Most guillotine leagues begin with 16 or 17 teams, without divisions or a fixed schedule, though you can adjust the league's size and timing based on preferences. While some fantasy platforms are built specifically for guillotine formats, virtually any platform can run one. For example, my longest running guillotine league is on ESPN, where the commissioner manually drops the eliminated team's players each week. In addition to that league, which is entering its eighth season, this season I am in multiple guillotine leagues at NFFC, home of the RotoWire Online Championship. In fact, if you'd like to compete against me, there are still openings on Aug. 29 at 8:30 p.m. EDT ($50 entry) and Aug. 30 at 10:30 p.m. ($200 entry).

Guillotine League Strategy & Advice

1.  Draft a balanced roster

While fantasy football draft strategy like "Zero RB" might work in traditional redraft leagues, a more balanced approach is better suited for guillotine formats. Prioritize building the strongest possible starting lineup in the early rounds and shift your focus to adding depth as the season unfolds.

It is critical that you know the league's roster settings. I have completed one guillotine league draft so far, and the running back pool dried up fast. However, in that league we only start two wide receivers, so there are plenty of receivers available, allowing drafters to put a premium on running backs. In my NFFC guillotine leagues, we start three wide receivers, so I expect the receivers' value and ADP to rise.

2.  Make "safe" draft picks

You don't need to have the highest-scoring team — just avoid finishing at the bottom. Rather than chasing high-risk, high-reward players, prioritize those with consistent usage. Focus on building a stable lineup with players who offer dependable, high-floor production. For example:

3.  Avoid pairing and stacking players who have early bye weeks

I have high hopes for Chicago with its upgraded coaching and offensive line, and I have drafted a lot of Caleb Williams, pairing him with DJ Moore or Rome Odunze in Best Ball and Redraft leagues. However, for guillotine leagues, their Week 5 bye is problematic. Unless you are very aggressive with waiver bids in the first month of the season, you probably will not be able to build enough depth to make up for multiple starting fantasy players sitting in Weeks 5 or 6. Nearly every Bears, Packers, Falcons, Steelers, Texans and Vikings player takes a slight dip in my rankings because of an early bye. For example:

4.  Pick players with favorable schedules, avoid players with tough schedules early in the season

I refer to RotoWire's Strength of Schedule tool to find advantages. It helps me find the best matchups using rankings that are adjusted for quality of opponent, and I can custom sort by any time period. For this exercise, I looked at the first four weeks:

  • Draft C.J. Stroud, who has the most favorable schedule for a fantasy quarterback in the first four weeks, over Justin Herbert, who faces some of the toughest matchups
  • Draft Travis Etienne, who has the second-most favorable early schedule for running backs, over Tyrone Tracy, who has the fourth-toughest early schedule
  • Draft Calvin Ridley, who has a top-10 early schedule, over George Pickens, who has the toughest series of early games for receivers

5.  Monitor injury reports and suspensions

This may seem obvious, but it's especially crucial in a guillotine league. With player depth being a concern during the early weeks of the season, a single poor performance could end your season. Therefore:

6.  Try to grab a top-5 TE.

Gain an advantage by focusing on a scarce position. With the early success of rookie tight ends in recent years, I don't feel as strongly about this strategy as I did in previous years because I believe there are more 900-yard potential tight ends than ever. However, in a league like this, the gap between the No. 5 tight end and the No. 17 is still significant. 

As teams are eliminated, you'll have ample chances to pick up high-end RBs and WRs from waivers. Consider these options:

7. Push QBs down the draft board

I absolutely want to have either Josh Allen, Lamar Jackson, Jayden Daniels or Jalen Hurts on my roster by midseason, but I won't draft any of them. I would rather draft positional players who I can count on to get targets or carries early in the draft. I feel confident that there are about 20 quarterbacks who will produce enough during the first few weeks to keep me alive, which means I wouldn't be surprised if I'm the last person to pick a QB in my guillotine leagues this season. 

8.  Act swiftly on the waiver wire when a team is eliminated and a top player at a position becomes available — but don't go "all-in" until late in the season

Allen, Jackson, Daniels, Hurts, Christian McCaffrey, Bijan Robinson, Saquon Barkley, Jahmyr Gibbs, Justin Jefferson, Ja'Marr Chase, CeeDee Lamb, Brock Bowers and Trey McBride are players that I want to get on my roster as soon as possible. However, I expect to compete deep into the season and need to make sure that I maintain a budget that will allow me to keep getting better every week. I avoid spending more than 25 percent of my budget on any one player during the first half of the season, unless I have an injury to one of my top players and am desperate to replace him.

Guillotine League Rankings: Top 150

RankNameTeamPosBYE
1Ja'Marr ChaseCINWR10
2Saquon BarkleyPHIRB9
3Bijan RobinsonATLRB5
4Jahmyr GibbsDETRB8
5CeeDee LambDALWR10
6Justin JeffersonMINWR6
7Derrick HenryBALRB7
8Amon-Ra St. BrownDETWR8
9Christian McCaffreySFRB14
10Ashton JeantyLVRB8
11Malik NabersNYGWR14
12Jonathan TaylorINDRB11
13Chase BrownCINRB10
14Josh JacobsGBRB5
15Brock BowersLVTE8
16Kyren WilliamsLARRB8
17Drake LondonATLWR5
18Nico CollinsHOUWR6
19Trey McBrideARITE8
20Brian ThomasJAXWR8
21De'Von AchaneMIARB12
22Bucky IrvingTBRB9
23A.J. BrownPHIWR9
24Ladd McConkeyLACWR12
25Puka NacuaLARWR8
26Breece HallNYJRB9
27James CookBUFRB7
28James ConnerARIRB8
29Garrett WilsonNYJWR9
30Alvin KamaraNORB11
31Omarion HamptonLACRB12
32George KittleSFTE14
33Chuba HubbardCARRB14
34Kenneth WalkerSEARB8
35Tyreek HillMIAWR12
36Lamar JacksonBALQB7
37Josh AllenBUFQB7
38Jaxon Smith-NjigbaSEAWR8
39Mike EvansTBWR9
40Tee HigginsCINWR10
41Davante AdamsLARWR8
42DK MetcalfPITWR5
43DJ MooreCHIWR5
44Tony PollardTENRB10
45David MontgomeryDETRB8
46D'Andre SwiftCHIRB5
47TreVeyon HendersonNERB14
48Jalen HurtsPHIQB9
49Terry McLaurinWASWR12
50Isiah PachecoKCRB10
51RJ HarveyDENRB12
52Aaron JonesMINRB6
53Marvin HarrisonARIWR8
54Jayden DanielsWASQB12
55Calvin RidleyTENWR10
56Tetairoa McMillanCARWR14
57Jameson WilliamsDETWR8
58Courtland SuttonDENWR12
59DeVonta SmithPHIWR9
60George PickensDALWR10
61Jaylen WaddleMIAWR12
62Jerry JeudyCLEWR9
63Xavier WorthyKCWR10
64Joe BurrowCINQB10
65T.J. HockensonMINTE6
66Sam LaPortaDETTE8
67Zay FlowersBALWR7
68Jakobi MeyersLVWR8
69Chris OlaveNOWR11
70Travis EtienneJAXRB8
71Rome OdunzeCHIWR5
72Tyrone TracyNYGRB14
73Kaleb JohnsonPITRB5
74Jaylen WarrenPITRB5
75Patrick MahomesKCQB10
76Travis KelceKCTE10
77Mark AndrewsBALTE7
78Baker MayfieldTBQB9
79Emeka EgbukaTBWR9
80Joe MixonHOURB6
81Ricky PearsallSFWR14
82Deebo SamuelWASWR12
83Travis HunterJAXWR8
84Rashee RiceKCWR10
85Jordan MasonMINRB6
86David NjokuCLETE9
87J.K. DobbinsDENRB12
88Kyler MurrayARIQB8
89Zach CharbonnetSEARB8
90Rhamondre StevensonNERB14
91Jauan JenningsSFWR14
92Stefon DiggsNEWR14
93Khalil ShakirBUFWR7
94Jake FergusonDALTE10
95Evan EngramDENTE12
96Josh DownsINDWR11
97Michael PittmanINDWR11
98Rashid ShaheedNOWR11
99Chris GodwinTBWR9
100Jacory Croskey-MerrittWASRB12
101Quinshon JudkinsCLERB9
102Jerome FordCLERB9
103Austin EkelerWASRB12
104Najee HarrisLACRB12
105Javonte WilliamsDALRB10
106Bo NixDENQB12
107Brock PurdySFQB14
108Matthew GoldenGBWR5
109Jordan AddisonMINWR6
110Jayden ReedGBWR5
111Tucker KraftGBTE5
112Dak PrescottDALQB10
113Jared GoffDETQB8
114Cooper KuppSEAWR8
115Caleb WilliamsCHIQB5
116Tyler WarrenINDTE11
117Justin FieldsNYJQB9
118C.J. StroudHOUQB6
119Drake MayeNEQB14
120Nick ChubbHOURB6
121Brian RobinsonSFRB12
122Cam SkatteboNYGRB14
123J.J. McCarthyMINQB6
124Dalton KincaidBUFTE7
125Trey BensonARIRB8
126Colston LovelandCHITE5
127Trevor LawrenceJAXQB8
128Dallas GoedertPHITE9
129Christian KirkHOUWR6
130Keenan AllenLACWR12
131Cedric TillmanCLEWR9
132Keon ColemanBUFWR7
133Hunter HenryNETE14
134Chris RodriguezWASRB12
135Kyle PittsATLTE5
136Chig OkonkwoTENTE10
137Darnell MooneyATLWR5
138Marvin MimsDENWR12
139Tank BigsbyJAXRB8
140Mason TaylorNYJTE9
141Joshua PalmerBUFWR7
142Braelon AllenNYJRB9
143Ollie GordonMIARB12
144Wan'Dale RobinsonNYGWR14
145Adam ThielenCARWR14
146Rashod BatemanBALWR7
147Hollywood BrownKCWR10
148Miles SandersDALRB10
149DeMario DouglasNEWR14
150Romeo DoubsGBWR5

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ABOUT THE AUTHOR
Steve has served several roles with RotoWire, starting as an intern working on breaking news and analysis and moving to NBA beat writer. Now a multi-sport contributor, he specializes in college fantasy football, guillotine league strategy and sports betting. He's also the undisputed best bowler at RotoWire and will be thrilled when fantasy bowling becomes a thing someday.
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