Cowboys vs Eagles Betting Odds, Picks and Predictions for Thursday Night Football
We finally have regular-season NFL games to bet on again! The 2025 season starts off with a Thursday Night Football matchup between the Eagles and Cowboys. Let's dig into the betting market and highlight some of the top options to consider.
Eagles vs. Cowboys Betting Odds
Eagles: Spread -8.5 (-105), -410 Moneyline (DraftKings)
Cowboys: Spread +8.5 (-115), +370 Moneyline (BetRivers)
Game Total: 47.5 points (DraftKings)
The Cowboys begin the season with star defensive end Micah Parsons no longer on the team. He was traded to the Packers following a contract dispute. A positive for the Cowboys is that cornerback Trevon Diggs (knee) is on track to play in their opener.
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Eagles vs. Cowboys Betting Picks
Saquon Barkley over 93.5 rushing yards (-110 DraftKings Sportsbook) for 1 Unit
The Eagles didn't ease Barkley into action last season, giving him 24 carries in Week 1 against the Packers. He finished the game with 109 rushing yards. It was the beginning of a special season that saw him rush 345 times for 2,005 yards. He finished with at least 100 rushing yards in 11 of his 16 games. In Week 10 against the Cowboys, the Eagles led 28-6 after three quarters. That contributed to Barkley receiving just 14 carries, which he turned into 66 yards. Cooper Rush started that game for the Cowboys.
Jalen Hurts did not play when the Eagles faced the Cowboys in Week 17. They leaned heavily on Barkley, who ran 31 times for 167 yards. Last season, the Cowboys allowed the third-most rushing yards per game in the league. With the expectation that Barkley at least approaches 20 carries in this game, he is in a favorable spot to thrive out of the gate.
Jalen Hurts under 18.5 completions (-121 DraftKings Sportsbook) for 1 Unit
The Eagles dominated last season with a +160 point differential that was the second-highest mark in the NFL. That didn't require them to throw a lot late in games. After attempting 538 passes over 17 games in 2023, Hurts finished with just 361 pass attempts over 15 games last season.
In his 15 games, Hurts completed fewer than 19 passes 11 times. When he faced the Cowboys in Week 10, he completed 14 of 20 pass attempts. Given the issues that the Cowboys should have on defense this season, the Eagles could score early and often in this game. If that happens, we might not see a ton of pass attempts from Hurts in the fourth quarter.
Dak Prescott over 36.5 pass attempts (-108 FanDuel Sportsbook) for 1 Unit
Prescott played eight games last season, one of which he left early. In the other seven games, he attempted at least 37 passes four times. In two of those games, he topped 40 pass attempts. While he did not play against the Eagles last year, he did face them twice in 2023. He attempted 44 passes in the first game against them, then 39 passes in the second game.
The Cowboys were lacking talent at running back last year, which forced them to rely heavily on the passing attack, even with Prescott missing so much time. They finished with the ninth-fewest rushing attempts and the third-most passing attempts in the league. In a matchup against the Eagles in which their defense might struggle to keep points off the board, Prescott should be forced to throw a lot.
Eagles vs. Cowboys Prediction
The Eagles went 8-1 at home last season. The Cowboys were actually better on the road, posting a 5-3 road record and a 2-7 home mark last season. The loss of Parsons should be huge for the Cowboys, especially since they allowed 27.5 points per game last season despite having the third-most sacks in the league. This is a big line for the Eagles to cover in Week 1, but they are the vastly superior team, so look for them to win in convincing fashion.
