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Best Bets for Detroit Lions vs. Baltimore Ravens | Baltimore Ravens -4.5 (-110)
Two of the top betting favorites to win Super Bowl LX square off tonight when the Detroit Lions travel to take on the Baltimore Ravens. Baltimore has owned Detroit in head-to-head matchups, including a 2-0 SU record since 2021.
New customers who sign up with Caesars Sportsbook Promo Code ROTO20X unlock 20 100% profit boost tokens. Register a new Caesars Sportsbook account before Monday Night Football kick off from M&T Bank Stadium tonight.
Oddsmakers are laying -4.5 with the Ravens as home favorites on Monday Night Football. The point spread opened at -6.0, moved to -6.5, then settled at its current -4.5 price.
The point total has steadily risen since an opening 51.5. Now, the point total is available at an inflated 53.5 line.
Both of these teams suffered disappointing Week 1 losses, before routing their divisional opponent at home in Week 2. There are no big injury concerns on either side, meaning we should get each offense at its best.
The Lions were shut down on offense during their first road game against Green Bay. Baltimore's defense bounced back against Cleveland after Josh Allen threw for nearly 400 yards in Week 1.
Until Detroit can prove itself against this team, the Ravens are currently a value play at -4.5 on the point spread. This is a much better price than -6.0 or -6.5, so lay the points with the home favorite, featuring a two-time NFL MVP quarterback and All-Pro running back, Derrick Henry, in Baltimore's backfield.
Best Bets for Detroit Lions vs. Baltimore Ravens | U 53.5 (-110)
The steam has pushed the point total to a big number at 53.5. In their last two matchups with Jackson under center, the Ravens and Lions have gone under this mark.
Baltimore routed Detroit 38-6 at home in 2023. They also went on the road and beat the Lions 19-17 in Week 3 during the 2021 NFL season.
Goff and the Lions' offense went ballistic against a bad Chicago defense. However, they are now playing in a hostile road environment against a John Harbaugh-led defense with playmakers at all three levels.
Conversely, Detroit edge rusher Aidan Hutchinson's presence off the edge will disrupt Jackson in the pocket, which could lead to miscues, like turnovers or inaccurate passes. The Lions have done a good job bottling up opposing running backs in 2025, limiting them to 4.1 YPC and two total rushing touchdowns.
Money is likely pouring in on the over due to the talent on each offense. The Ravens scored at will against Buffalo but got off to a slow start against an underrated Cleveland defense.
53.5 is a lot of points, especially in a prime-time game. Let's bet under 53.5 at -110.
Best Bets for Detroit Lions vs. Baltimore Ravens | David Montgomery Anytime TD Scorer (+125)
Don't forget about David Montgomery's usage in Detroit's backfield. He's totaled the same number of carries as Jahmyr Gibbs (22) in two different game scripts.
Montgomery is most effective inside the red zone, especially at the goal-line. He's a power runner who could take advantage of the Lions moving the football downfield. Baltimore's defense contained James Cook and the Bills' run game in Week 1, yet they couldn't keep him or Josh Allen out of the end zone as ball carriers.
The Lions' offense will wind up in the red zone a few times. As a result, Montgomery will receive high-value touches, scoring a touchdown for the second consecutive week at plus odds.
Detroit Lions vs. Baltimore Ravens Picks
- Baltimore Ravens -4.5 (-110)
- U 53.5 (-110)
- David Montgomery Anytime TD Scorer (+125)
Best Events to Use the Caesars Sportsbook Promo Code ROTO20X For on September 22nd
- NFL: Detroit Lions vs. Baltimore Ravens. An interconference matchup between two of the 2026 Super Bowl favorites. Star players include Lamar Jackson, Derrick Henry and Zay Flowers against Jared Goff, Jahmyr Gibbs and Amon-Ra St. Brown.
- MLB: Milwaukee Brewers vs. San Diego Padres. The Brewers hold the best record in the National League with 95 wins and have clinched a playoff berth. San Diego is currently in the second NL Wild Card seed.
- MLB: St. Louis Cardinals vs. San Francisco Giants. These two National League opponents are in desperation mode, each sitting at four or five games behind the New York Mets for the final NL Wild Card seed. A combined 5-15 record across their last 20 games played.
