Champions League Best Bets for Wednesday, October 22: Picks & Predictions
Wednesday's Champions League slate features several marquee matchups across Europe with plenty of betting value. From a goal-heavy clash expected between Frankfurt and Liverpool to Harry Kane's scoring odds against Club Brugge, we've highlighted four of our favorite plays for the day, including angles on Atalanta and Real Madrid.
Knowing injuries and predicted lineups (and eventually confirmed) for Champions League matches is always useful before betting matches. Check out our lineups page to get all the info.
UEFA Champions League Best Bets for Liverpool at Eintracht Frankfurt
Over 3.5 total goals +100
Eintracht Frankfurt's matches this season season have been full of goals, as nine of their 10 competitive games have featured at least four goals. The one time that didn't happen was a 3-0 defeat against Bayern Munich, so it's clear that there will be goals every time Frankfurt step on the pitch. Liverpool might be coming off a 1-0 loss to Galatasaray in their previous Champions League contest, but more often than not, their matches have also had plenty of goals.
Even though they've found the back of the net just three times during their ongoing four-game losing skid across all competitions, Liverpool simply have too much attacking potential to continue struggling upfront. With Florian Wirtz, Cody Gakpo, Alexander Isak, Hugo Ekitike, Mohamed Salah, there's just too much talent for the Reds to continue under performing in front of net. Considering that both clubs are desperate to bounce back, this should be a back-and-forth contest that could end up with more than 3.5 goals.
UEFA Champions League BTTS bet for Juventus at Real Madrid
Both teams to score - yes -127
Real Madrid have one of the best attacks in the world, led by Kylian Mbappe and Vinicius Junior, so they're a good bet to score against any team. Los Merengues have found the back of the net in each of their 11 competitive matches this term, and at least twice nine times over that stretch. They should be able to take advantage of some of the defensive shortcomings Juventus have shown of late.
The Old Lady opened their Champions League campaign with back-to-back draws against Dortmund (4-4) and Villarreal (2-2), so conceding six times in a two-game stretch isn't the ideal scenario before a trip to the Santiago Bernabéu. Considering that seven of Juventus' last ten Champions League away matches saw both teams score, that trend could occur again Wednesday.
UEFA Champions League Bets for Slavia Prague at Atalanta
Atalanta to cover -1 spread -147
Atalanta deserved better luck in their recent scoreless draw with Lazio in Serie A, but that has been the case almost every time they've played at Gewiss Stadium this season. Even though La Dea have had plenty of problems capitalizing on their chances, they've posted an xG of at least 1.85 in each of their five games at home across all competitions this term. They should deliver another dominant performance against a Slavia Prague that doesn't have the talent to keep up.
Slavia Prague have posted an underwhelming European record against Italian clubs, losing nine of ten in all competitions (D1, L9), including a 3-0 loss to Inter Milan last time in the Champions League. Everything is shaping up for Atalanta to win this game by a multi-goal margin, even if they've done that just once at home this season.
Club Brugge at Bayern Munich Betting Odds & Goalscoring Bet
Harry Kane to score first goal +225
Given his impressive record of 22 goals in 16 competitive appearances in all competitions to start the campaign, is anyone brave enough to bet against Harry Kane scoring a goal every time he leads the attack? As good as Kane has been in the final third, the Englishman has also been decisive and tends to open the scoring, as he's scored Bayern's first goal in five of the club's 11 matches in all competitions.
Even though Kane has yet to score the first goal in back-to-back games this season, he looks poised to break the deadlock again here, just like he did in Der Klassiker. Considering the defensive shortcomings Brugge have shown, both at the domestic and European level, there's little hope they can stop the top striker in Europe.
Tottenham at Monaco Corners Bet and Upset Pick
Champions League Betting Picks Wednesday, October 22
- Eintracht Frankfurt vs. Liverpool: Over 3.5 total goals +100
- Real Madrid vs Juventus: Both teams to score -127
- Atalanta vs. Slavia Prague: Atalanta to cover -1 spread -147
- Bayern Munich vs. Club Brugge: Harry Kane to score first goal +225
Visit RotoWire all season for exclusive sports betting picks and our weekly Premier League betting show. Remember that betting apps vary in terms of odds, so we have an easy-to-use odds page that allows you to shop for the best lines at DraftKings, FanDuel, BetMGM and PointsBet. Claim over a thousand dollars in bonuses by signing up at the best sports betting sites using the best sportsbook promos.
