With tonight's DraftKings NBA DFS main slate featuring four matchups and several key names on the NBA injury report, building winning lineups starts with understanding rotations, usage trends and matchups. This DFS breakdown leans on NBA projections, recent NBA player stats and expected starting lineups to highlight elite plays, mid-range targets and value options. From stars positioned to exploit defensive weaknesses to salary savers stepping into larger roles due to NBA injuries, this guide connects the latest NBA news with actionable lineup insight. Whether you're tracking fantasy basketball rankings, searching for DFS sleepers, or fine-tuning roster construction, these picks are designed to maximize upside across tonight's slate.
Try our DraftKings NBA Lineup Optimizer to discover more expert recommendations, customize the player pool, set exposure percentage and mass-enter DFS lineups.
DraftKings Main Slate NBA Games Today
NOP at IND: Pelicans 3-15 on road; Pacers 3-7 in last 10 games, 7-16 at home
CLE at PHI: Cavs 9-9 on road; 76ers 10-10 at home; both teams 6-4 in last 10 games
CHI at BKN: Bulls 7-12 on road; Nets on five-game slide
LAC at TOR: Clippers 8-2 in last 10 games; Raptors 7-3 in last 10 games, 13-9 at home
For the latest spreads and over/unders, visit RotoWire's NBA Odds page. There you can also find player props, futures, picks, articles and sportsbook bonus codes.
NBA Injury Report Today
For all the latest updates, visit RotoWire's NBA Injury News page and our comprehensive NBA Injury Report.
NOP - Jose Alvarado (oblique), Herbert Jones (ankle): OUT
IND - Bennedict Mathurin (thumb): OUT
CLE - Darius Garland (toe), Sam Merrill (hand), Dean Wade (knee): OUT
PHI - Dominick Barlow (back): OUT
CHI - Josh Giddey (hamstring): OUT
BKN - Ziaire Williams (illness): OUT
LAC - John Collins (groin), Kawhi Leonard (ankle), Ivica Zubac (ankle): Questionable; Derrick Jones (knee): OUT
TOR - Immanuel Quickley (back): Questionable; RJ Barrett (ankle), Jakob Poeltl (back): OUT
Elite NBA DFS Picks
Guards
James Harden, Clippers 
($9,800) at Raptors
Harden continues to fill the stat sheet, averaging 25.4 points, 4.6 rebounds, 8.0 assists and 1.8 steals over the last five games, producing a high of 62.5 DK points in that span. He is averaging 3.5 more points per game on the road compared to at home this season, and he should do well against the Raptors, who are giving up the league's seventh-most points per game to opposing point guards and are also dealing with a bit of injury trouble.
Donovan Mitchell, Cavaliers 
($9,600) at 76ers
Mitchell is averaging 27.1 points, 5.4 rebounds, 6.1 assists and 1.9 steals over the last 10 games, surpassing 50 DK points five times across that span. He faces the second of back-to-back meetings against the 76ers, after he racked up 35 points, seven rebounds, nine assists and a steal for a total of 61.3 DK points in the last game. He has another good chance to pad his stats, as the Sixers give up the league's fourth-most free throws to opposing shooting guards.
Forwards/Centers
Michael Porter, Nets 
($8,900) vs. Bulls
Porter is averaging 25.4 points, 7.4 rebounds, 3.2 assists and 1.6 steals over his last five outings, going over 40 DK points four times, including a high of 50.8 in that span. He has a great chance to prosper against the Bulls, who are giving up the league's eighth-most points and third-most rebounds per game to opposing small forwards. Porter also racked up 61.5 DK points in his previous encounter with the Bulls, back in early-December.
Pascal Siakam, Pacers 
($8,700) vs. Pelicans
Siakam is averaging 24.9 points, 7.4 rebounds, 4.0 assists and 1.2 steals over the last 10 games, finishing with fewer than 35 DK points just once and topping 44 six times within that period. He faces a favorable matchup against the Pelicans, who are giving up the league's fourth-most points in the paint, along with the eighth-most points, including the fifth-most three-pointers per game to opposing power forwards.
Nikola Vucevic, Bulls 
($8,200) at Nets
Vucevic is averaging 20.0 points, 9.4 rebounds, 4.5 assists and 0.9 blocks across the last 10 games, including going over 50 DK points in three of the last six. He is up for a good chance to deliver against the Nets, who are giving up the league's eighth-most points in the paint, along with the third-highest field-goal percentage and 10th most free throws per game to opposing centers.
Expected NBA DFS Chalk
Trey Murphy, Pelicans 
($8,100) at Pacers
Murphy is amidst his hottest stretch of the season, averaging 32.6 points, 6.8 rebounds, 4.0 assists and 1.4 steals over his last five outings, including a season-high 42-point effort and going over 60 DK points twice in the last four games. He has a great chance to keep rolling against the Pacers, who are giving up the league's second-most points, second-most rebounds and most free throws per game to opposing shooting guards.
Mid-Range NBA DFS Picks
Andrew Nembhard, Pacers ($7,200) vs. Pelicans
Nembhard is averaging 17.3 points, 3.4 rebounds, 8.5 assists and 1.3 steals over his last 10 outings, surpassing 30 DK points eight times, with a high of 56.0 over that span. He should continue to rack up numbers against the Pelicans, who give up the league's third-most points per game, in addition to allowing the fourth-highest opposing field-goal percentage.
Ayo Dosunmu, Bulls ($5,600) at Nets
Dosunmu is averaging 14.7 points, 3.3 rebounds, 4.9 assists and 1.1 steals over the last 10 games, reaching a high of 45.0 DK points within that period. He should continue to see a boost in opportunity due to the absence of Josh Giddey, and he has a good chance to flourish against the Bulls, who give up the league's fourth-highest three-point shooting percentage and second-most steals per game to opposing shooting guards.
Saddiq Bey, Pelicans ($5,700) at Pacers
Bey topped 20 DK points in back-to-back starts since returning from a six-game absence. He is averaging 15.1 points, 5.8 rebounds, 2.3 assists and 0.9 steals on the season and should do well against the Pacers, who give up the league's most rebounds and fourth-highest field-goal percentage to opposing small forwards.
NBA DFS Value Picks
Kelly Oubre, 76ers 
($4,900) vs. Cavaliers
Oubre is averaging 5.8 points, 4.6 rebounds, 1.2 steals and 0.8 blocks with a high of 32.3 DK points across five games since returning from a six-week absence. He is shooting 40 percent on 10 three-point attempts over the last three outings and has a good chance to keep that going against the Cavs, who give up the league's second-highest three-point percentage to opposing small forwards, along with the league's 10th-most points and eighth-most free throws per game.
Yves Missi, Pelicans ($4,500) at Pacers
Missi logged 12 points and 12 rebounds in the last game for his first double-double since late-November. Nonetheless, he is averaging 7.0 points, 7.4 rebounds, 1.6 assists and 1.4 blocks over the last five games and could prosper against the Pacers, who give up the league's fifth-most points in the paint.
