Injury hotspots for Week 8 include the Cowboys' secondary, Bears' secondary, Giants' secondary, Bucs' skill-position players and Texans' wide receivers.
Below you'll find four different categories, with our lists including key offensive linemen and defensive players whose absences might impact fantasy decisions. The bottom section, for potential game-day decisions, is sorted by kickoff times. It can be used as a checklist/cheatsheet for Sunday morning and afternoon when inactives come out and we need to adjust lineups. Before we get to the 'questionable' players, let's see who's definitely in and who's definitely out...
Good to Go 💯
QB Baker Mayfield (knee)
RB Josh Jacobs (calf)
RB D'Andre Swift (groin)
RB Alvin Kamara (ankle)- WR Chris Olave (ankle)
WRs Terry McLaurin (quad) & Deebo Samuel (heel)
WR Jaylen Waddle (hamstring/rest)- WR DJ Moore (groin)
WR Stefon Diggs (chest)- WR Emeka Egbuka (hamstring)
WR Josh Downs (concussion)
WR Jerry Jeudy (knee)
WR Darius Slayton (hamstring)
WR Curtis Samuel (ribs)
TE Dalton Schultz (back/shoulder)- TE Juwan Johnson (neck)
TE Tanner Hudson (concussion)
#Commanders WRs Terry McLaurin and Deebo Samuel Sr. were full participants in practice again today and are on track to return to action Monday night at Kansas City.
— Tom Pelissero (@TomPelissero) October 24, 2025
Ruled Out/Doubtful 🚑
Out/Doubtful/IR
- QB Jayden Daniels (hamstring)
QB Bryce Young (D - ankle)
QB Brock Purdy (toe)- RB Bucky Irving (shoulder/foot)
- RB Roschon Johnson (back)
- RB Kendre Miller (IR - ACL tear)
- WRs Mike Evans (IR - collarbone) & Chris Godwin (fibula)
- WR Ricky Pearsall (knee)
- WRs Nico Collins (concussion) & Christian Kirk (hamstring)
WR Garrett Wilson (knee)
WR A.J. Brown (hamstring)
WRs Calvin Ridley (hamstring) & Bryce Oliver (knee)- WR Joshua Palmer (knee)
- WR Dontayvion Wicks (calf)
WR Scotty Miller (finger)- TE Cole Kmet (back)
- TEs Darren Waller (pec) + Julian Hill (ankle)
Potential Workload Beneficiaries (From Injuries Above)
- QB Marcus Mariota
- QB Andy Dalton
- QB Mac Jones
- RBs Rachaad White & Sean Tucker
- RBs Alvin Kamara & Devin Neal
- WRs Emeka Egbuka, Tez Johnson & Sterling Shepard
- WR Kendrick Bourne
- WRs Jaylin Noel, Jayden Higgins & Xavier Hutchinson
- WRs Josh Reynolds (Q), Arian Smith, Allen Lazard & Tyler Johnson
- WRs DeVonta Smith, Jahan Dotson & John Metchie
- WRs Elic Ayomanor, Chimere Dike & Van Jefferson
- WRs Keon Coleman & Curtis Samuel
- WRs Matthew Golden (Q), Christian Watson (Q) & Malik Heath
- TE Colston Loveland
- TE Tanner Hudson & WR Malik Washington
Key Defensive Players + Offensive Linemen
- CB Sauce Gardner (concussion)
CB Trevon Diggs (concussion) + S Donovan Wilson (arm)- CB Paulson Adebo (knee) + S Jevon Holland (D - knee)
LB Divine Deablo (arm) + DB Billy Bowman (hamstring) + OLB Jalon Walker (groin)- DT Jeffery Simmons (hamstring)
- OLB Haason Reddick (knee) + RG Luke Haggard (shoulder)
- C Jake Brendel (hamstring) + DE Bryce Huff (hamstring)
- CB Kyler Gordon (groin) + CB Tyrique Stevenson (shoulder) + LT Braxton Jones (knee)
- CB Adoree' Jackson (concussion) + C Cam Jurgens (knee)
Listed as Questionable - Should Play 👍
- QB Tyrod Taylor (knee)
- RB D'Andre Swift (groin)
- K Cairo Santos (thigh)
- K Graham Gano (groin)
The question with Taylor is less about availability and more about whether he's Aaron Glenn's choice as the starter. Health could play a role in the decision, but it seems like Taylor will at least be available as the backup. ESPN's Rich Cimini has been reporting all week that Taylor is the favorite to start. Glenn, meanwhile, told reporters that he decided early in the week but is trying to keep it a secret. He maintained that stance Friday, declining to name his Week 8 starter.
Truly Questionable / Game-Time Decisions 🤔
Early Games
- QB Michael Penix (knee)
QB Lamar Jackson (hamstring)- RB Breece Hall (knee)
- RB Tyler Allgeier (hip)
- WR Josh Reynolds (hip)
- TE Dalton Kincaid (oblique)
- TE David Njoku (knee)
- TE Mason Taylor (quad)
Most of these guys will play, but only Jackson and Hall were full practice participants Friday. Penix was listed as limited all week, and he may be treated as a game-time decision. Ravens coach John Harbaugh said he will start QB Tyler Huntley, rather than Cooper Rush, if Jackson doesn't end up playing.
QB Michael Penix Jr. (knee) is questionable for Sunday. Coach Raheem Morris said he still feels good about Penix playing, but they'll take it to game day.
— Marc Raimondi (@marcraimondi) October 24, 2025
Late-Afternoon Games
There aren't any fantasy-relevant players listed as questionable for the three late games this week.
Primetime Games
- WRs Matthew Golden (hip) + WR Christian Watson (IR) + K Brandon McManus (quad)
RB Kareem Hunt (knee) - MNF
Golden was an end-of-week addition to the injury report, listed as questionable after a limited practice Friday. Watson, meanwhile, will need to be activated from IR on Saturday in order to play Sunday. He's listed as questionable, after remaining limited in practice all week (perhaps a hint that he's another week or two away still?).
Key Defensive Players + O-Linemen
- DT Vita Vea (foot)
- LBs Matt Milano (pec) + Terrel Bernard (ankle)
- CB Deommodore Lenoir (quad)
- DE Trey Hendrickson (hip)
- S Xavier Woods (ankle) + OLB Arden Key (quad)
- S Juanyeh Thomas (migraine) + LT Tyler Guyton (glute)
- C Zach Frazier (calf)
- LT Josh Simmons (personal) + RG Trey Smith (back)
